Treatment for Hole in the Side/Aeromonas?

FacelessMasses

AC Members
Nov 1, 2008
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Hi everyone,

I'm sad to be back so soon with another sick fish. I'm starting to think we're cursed. :-( But cursed or not, I want our fish to get better, so here I am again!

We currently have a betta who isn't doing too well (http://www.aquariacentral.com/forums/showthread.php?t=171759). I'm keeping up on water changes, and am following the advice I have gotten.

But we have a zebra dannio (glofish actually) with what appears to be "hole in the side" or "aeromonas" according to the internet research I've done. We had a previous dannio die of what appears to be the same problem, but at that time were unable to determine what it was that killed him. Most of what I read described this disease in koi, but I did find references to other freshwater fish.

It started in the previous fish as, well, a hole in his side. It kept eating away at him, and he developed a fungal infection. We treated the fungal infection, but antibiotic treatments did nothing for the hole in his side. (That was 4 or 5 months ago). Unsure if that was because the disease was too far advanced.

This morning I noticed another fish who had lost scales on his side, and ran to the internet to get more info. I found "hole in the side" disease, but the treatments I've read are contradictory and I don't know what to do. I have him in a salt bath at the moment (4 tsp to 1 gallon of aquarium water), and will take him out after 30 minutes. I read I could use hydrogen peroxide, iodine, or even neosporin to treat the wound directly (not sure about that one). And I can use some fungal medication to prevent that sort of infection. But no one seems to agree whether an antibiotic added to the water will help.

Info:
Water: Ammonia - 0ppm, Nitrites - 0ppm, Nitrates - 15-20ppm, temp is kept at 78 with heater currently. Been doing a 33% water change and cleaning of the gravel every two weeks, but have been considering increasting to 25% water change weekly with a cleaning every other week (as the fish don't seem to be doing too well). Have had the tank up and running with current fish for about a year.

Fish: Zebra Dannio (glofish). Had it over a year. 5mm circular area on side where scales are missing and muscle is showing. Also showing white spot on bridge of nose and tendency to skim along the top of the water recently. Missing scales were noticed this morning but not within the last several days.

Treatment so far: Removed to quarantine tank with mechanical filtration. I'll be purchasing a small heater for the quarantine tank later today (it doesn't get below 74 degrees, but I read that warmer water would be best while he heals). Performing a 30 minute salt bath.

I did a search of the forums for "hole in the side" but the search gave me everything for "hole" and "side" and I couldn't find anything useful - hence the post. Thanks for the help!

-Facelessmasses
 
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OK. Aeromonas are not fungi, they're bacteria, so are not susceptible to pure antifungal treatments, nor, to any degree, to aquarium salt.

Untergasser recommends Flurazolidone; this you're unlikely to be able to get, and so you're looking for a commercial medication which specifically mentions Aeromonas. Chloramphenicol should also work. Again, you probably can't get them as pure drugs, but look for them on the packaging if you're lucky enough to have ingredients listed.

However, Aeromonas does not usually present in this way; generally it's a pathogen associated with finrot. It's sometimes found with Vibrio, which does present as skin haemorrhages. However, I'd be more inclined to be concerned that the hole in the side is of traumatic origin (what are the fish's tankmates?), or tuberculosis. In either case, Aeromonas might well be found as a complication, but not the root cause.
 
Thanks for the quick reply and the condolences.

Chloramphenicol - got it. Thanks! When I head to the LFS today I will read ingredients. I would be happy to find something that mentions "hole in the side" like most medications mention "hole in the head" but I don't think I've ever seen that listed. Plus when every medication sold, regardless of ingredients, seems to treat the exact same issues - it's very confusing as to what to buy.

I wasn't adding any anti-fungal treatment to treat the "hole in the side," only to treat any secondary fungal infections which might occur, and which did occur the last time we had a fish which had this sort of issue.

As for the salt, I knew it was useful for parasites and one of the sites I went to mentioned a salt bath for this condition (hole in the side) specifically. I was hoping that as this disease was caused by bacteria - either Aeromonas, pseudomonas, etc. - that bacteria would not do well in high salt concentration, and it might be beneficial. Of course everything one reads on the internet is true, right? :-) Well, at least any (so far) non-visible parasites will have had a bit of a shock.

Also, most of the sites I went to listed "Hole in the side" as the common name for issues coming from Aeronomas - which is the reason I mentioned the name. I don't know specifically what the bacteria is, only that something is eating away at his side, and every other treatmet we tried with the other fish that died of this (tetracycline, erithromiacin, anti-fungal (he did have a secondary fungal infection), and other "all in one" cures) didn't have any effect.

The fish's tankmates are other dannios, a total of 4 were in the tank (10gal) and we were adding a 5th today which has been in a quarantine tank for a few weeks. It was when I was transferring the new fish that I noticed the issue with the fish in question. They chase each other, but I've never seen them get terribly aggressive towards one another.
 
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