Racking my own brain before getting my own UV, I did come up with the following three 'negatives' in regard to UV overkill. First, every watt of UV light is also a watt of continuous electric heat being added to your tank water. In an overkill situation on an aquarium tank, say your 36 watts of continuous water heating might become an issue i.e. needing a chiller to keep the tank from overheating. I discovered this issue as a result of already running a submerged power head/circ pump, which is already acting as an 'unwanted' source of extra electric heat.
Second, every UV unit is designed with a certain flow rate in mind. If you use that UV unit at a lower flow rate continuously, to avoid creating a maelstrom in your tank, in theory this could lead to potential problems in terms of internal temperature rise of the UV unit, degrading of the plastic assembly etc. Again I really don't know if this actually does have any bad long term side effects of any kind, or if I'm just being a paranoid sort of girl when it comes to hardware designs. Based on the fact that the turbo twist unit you're considering uses the same basic body for different lamp ratings, it's probably not an issue at all.
Lastly, UV can't distinguish between 'good' and 'bad' bacteria. Therefore running a really strong UV all the time can knock down the mobile 'good' bacteria count as well as the bad.
In my own case I went with 'only' an 8 watt UV unit on my 55 gal tank ... mostly to avoid the risk of tank overheating without a chiller. But I also picked a UV with a very large body so the relative exposure time is high (my Rainbow Lifegard body probably holds over a quart of water, versus the turbo twist body holding a few ounces). I also only run the UV two days a week ... in each case for 24 hours after my water changes to kill off any potential 'illegal immigrants' ... and then shut it off for the next 48 hours. In the event that I develop an ick/bad bacteria problem in the future, I installed my UV with a bypass valve and hose so that I can temporarily run it at say 1/4th or 1/6th of the rated flow to seriously 'zap' those nasty bugs with UV for a week. At 1/4th or 1/6th flow it will take say an hour to run all of my tank water through the UV instead of the usual 10-15 minutes, but after a couple of days those bugs will still be just as dead. But so far since installing the UV I have had zero algae or ick/bacteria problems so I have yet to actually test my theory in practice (and hopefully I never will).
PS I also run a 1 micron post-filter after my UV in my main filter 'loop', to try and pick off some of the 'dead bodies' before they get dumped back into my tank. It was surprising how much gray-black 'slime' builds up on the 1 micron filter pads after a while.
PPS I also run a totally separate HOB filter with bio-wheels to prevent the UV from directly 'pre-sterilizing' the bio-wheel water. I have no idea whether doing this is actually accomplishing anything, but I wanted extra tank flow anyhow and it can't do any harm.
PPPS I also park any 'new arrivals' in a 6 gal isolation tank for at least a couple of weeks after bringing them home, to make sure they won't act as a source of potential bacteria infection once moved to my 55 gal tank. IMHO an 'ounce of prevention' is worth an extra 28 watts of UV !
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