I have the Tetra 5W in my 30 gallon cichlid tank. It kills bacterial and algal bloom and diseases such as ich that free-float in the water, but anything in your filter, sand, etc is not harmed, just the free-floating stuff. It does not kill ich on an infested fish. It helps if you tend to overfeed or overload your tank, but it's not necessary if you are careful. The 5W is about the smallest unit you can get, and not good beyond around 30 gals. For SW reef I don't think it is a good idea, as it will sterilize the live nutrients your corals and inverts eat.