drill speed for acyrilic?

I've used a hole saw (slowly----very slowly) and cooled it with water.

If you can- Start at the top and finish it from the inside. This will prevent it from splintering when it pops through.
 
I agree with rallysman, drill with a holesaw very very slowly and make sure the bit isn't blunt. To stop splitting or chipping I clamp a piece of wood on the opposite side to the drilling.
 
Slow speed and sharp bit. That clamping a pice of thin wood on the exit size works great!
 
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