The question was not answered. The questioner asked if Prime will remove mercury from salt water. RO cannot be used in salt water. The answer, I think, is 'maybe', depending on how much mercury is involved, and what the concentration is. Just a guess, but if the mercury in question came from a broken thermometer/hydrometer, there is a good chance it's not mercury at all. Mercury stopped being used for such purposes years and years ago. Most weighted aquarium devices use small iron balls, virtually harmless in an average size marine aquarium, especially if it's fish only, and will cause no harm. A small coral aquarium simply needs a water change. The iron balls rust away quickly, and will always settle at the lowest point. Prime is a superlative product, btw. Polyfilters may be a better choice for heavy metals.
This is a more verbose reiteration of what I said earlier and is, unfortunately, just as vague as the product description. Their answer, as well as yours, does not really provide that much info on the matter. The product only detoxifies mercury in "typical tapwater levels." Seeing as how this amount varies up until the acceptable cutoff, it is still quite vague, making it impossible to give a decent answer.
In short, RO/DI water will always be a better alternative. You must be confusing marine aquaria with freshwater, as RO/DI water can be used and is more commonly used for this purpose. RO/DI filtration will always remove more than any dechlorinator, which is why it is highly recommended for tanks with much more sensitive invertebrates. Prime also does not remove any algal nutrients, like phosphate, that are a major concern.
Many thermometers, especially precision ones (though not ones commonly used by aquarists) are still made with mercury. If a thermometer did break, then the iron balls are an issue, as well. Most of the time, iron is not the only metal included and can be toxic to many invertebrates. They will need to be removed and
not allowed to rust away. Polyfilters can and do work, but I recommend a specialized adsorption resin. It is what is included in polyfilters, except in its pure form. It is also regenerable, unlike the disposable polyfilters, making it a much better choice. Then again, the OP could be worried about mercury that is in many local tap sources, which builds up in organisms' systems over time, making the concern somewhat valid. Again, an RO/DI unit will remove all of this.