Will a AquaClear 110 work for a 40 gal?

The 110 pumps 500gph, the 70 pumps 300gph. Allowing for substrate and decorations a 40 gallon tank likely only holds around 30 gallons of water. For a light-medium stocking level the tank volume should be circulated about 5x/hour, for a heavy stocking level (like Malawi mbuna) up to 10x/hour is better. Unless you're doing a hillstream tank the 110 would definitely be overkill.
 
The 110 pumps 500gph, the 70 pumps 300gph. Allowing for substrate and decorations a 40 gallon tank likely only holds around 30 gallons of water. For a light-medium stocking level the tank volume should be circulated about 5x/hour, for a heavy stocking level (like Malawi mbuna) up to 10x/hour is better. Unless you're doing a hillstream tank the 110 would definitely be overkill.

Hill stream? Sorry newish to fish. I plan on fully stocking it


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Replace the sponges when they start to fall apart, otherwise just rinse them weekly in a bucket of tank water when you do partial changes.
 
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