First off, I feel a bit guilty joining a forum for the sole reason of asking for help... but I'll get probably get over it. I could probably be convinced to stick around. For now, I'm just looking for some guidance on a couple of sick goldies. I apologize if the following info is overkill, but I like to provide any background that might help. I have an established 75 gallon, 2-year old, cold freshwater tank for goldfish and dojos. It is overstocked (I know). I have tabooed by mixing fancies and commons (I know). The stock is as follows: - 1 large Common - 2 large Comets (the sickies) - 1 large Shubunkin - 1 medium calico ryukin - 1 medium red ryukin - 2 small chocolate orandas - 3 full-size dojo loaches - 2 small golden dojo loaches - 1 Pleco (about 4 inches, and growing like an SOB). Features a couple of mopani wood pieces, various plastic plants, and a castle. The loaches are often nowhere to be found for all the hiding places. The gravel is a bit coarse for their liking though. Equipment: - Single tube standard flourescent hood - Fluval FX-5 Canister - Aquaclear 300/70 HOT - Two bags of Fluval nitrate remover in the Aquaclear. They don't solve my nitrate issues, but I keep them around to sort out the tannins from my mopani wood. Water test levels are Temp: Warm Canadian weather (!) has pushed it as high as 80F in the last week. This might have worsened things. Typically 72-76F. O2: >7 ppm Ammonia: 0 Nitrite: 0 Nitrate: >80ppm. This despite weekly 25% water changes. I've cut back on food and started twice-weekly changes to try and reign this in. (I'm also plotting to build a denitrator, but this probably won't help in the near future). So basically, I live in the boondocks where the only aquarium fish store within 100 miles is a Walmart. I've long since learned how reliable those offerings are (though all the large goldfish came from there about 2 years ago). So I happened to be out of town a couple weeks ago, and found myself near a Petsmart. I got a bit overexcited upon seeing more than 2 kinds of fish, which explains the overstocking problem. (You see, believe it or not, I just got rid of a 14" Koi last month, so the tank seemed spacious by comparison). About a week after the Petsmart fish (orandas, ryukins, golden loaches) were introduced, I've got a problem that only seems to have afflicted the comets and their long flowy fins. This is what the more advanced case looks like today: The disease seemed to take the following steps: 1) The thin translucent fins (mainly the tail at first) seemed to develop a series of opaque whitish spots throughout. These develop some depth to them, like growths. 2) The red vessels, already partially visible, became much more pronounced. The ventral and anal fins became involved, and were turning rosy or red in large areas (septicemia?) 3) The white spots seem to come to a reddish head, and seemed to hemmorage, often leaving holes and rips behind. The weakened fins are obviously prone to tearing. The fish are behaving and feeding normally, but seem a bit anemic. So far, I've tried the following: 1) For the last week, the fish have fed on Goldfish Connection Medi-Gold. 2) I initially tried a parasite tab medication I found at Walmart ("Jungle" brand). This ran full strength for 3 days, and half strength following a water change. This might have had some minor affect on the spots of one of the comets, but may have been coincidence. It might also have been a crappy product. 3) I have tried low levels of API super Ick Cure, but haven't been fully dosing the tank for fear of harming the loaches. This doesn't seem to have had an affect. 4) For lack of success from medication, I've resorted to daily water changes to try and manage the nitrate levels, and possibly reduce any parasite that is present. Any suggestions would be appreciated. Thanks all.