The AC 2250 is a relatively old design, and I think you would have some better alternatives available to you which would be both easier to maintain and better filtration alternatives. I have several 2260's myself, and have to say they are no longer my favorite canisters, although they are BIG, BIG, BIG.
Although some of this would depend on the kinds of fish you are planning on keeping in your tank, a Fluval 404 (or the equivalent Eheim product), plus one or two Aquaclear 500's, would give you excellent biological and mechanical filtration. You would load the canister with only bio materials (i.e. noodles and bioballs) and put a prefilter on the intake to reduce the amount of gunk that gets into the canister (because it is harder to clean a canister than an Aquaclear). Then use the Aquaclears primarily for water circulation and mechanical filtration. Load the Aquaclears only with sponges, and rinse them out thoroughly and frequently. This will remove solid waste from your tank quite effectively.
Good luck with your new tank.