reptileguy2727 said:
i was thinking about it, and i have never heard that meds become more toxic at higher levels, not in books, online, forums, anywhere. im not saying it is impossible, but do you have any info on it from a good website or a book? i know that many people use just salt and heat to treat ick, but i prefer meds, i have found them to be more reliable.
When the manufacturer -- in this instance Kordon -- of the drug puts cautions of that nature on their web site, I tend to sit down and make note:
Re: Malachite Green
"TOXICITY
The toxicity of Malachite Green varies with a number of factors including species of fish and its size, and less with prevailing water conditions. Malachite Green can be used at concentrations of 0.05-0.15 ppm. Used at 0.05 ppm, most species can be treated with little if any toxicity problems. However, care must be exercised when treating known sensitive fishes such as dwarf cichlids, barbs, tetras, gouramis, livebearers, catfish, loaches, mormyrids and scaleless fishes. Keep the fishes being treated under close observation and stop treatment, filter the water with activated carbon and perform a water change if any undue signs of stress are noted. AmQuel can be used to reduce treatment concentrations. Caution must always be exercised when using this product at dosages higher than 0.05 ppm. It is recommended that the literature be consulted in such cases for additional information on treatments.
Water conditions in general do not significantly influence the toxicity of the drug and therefore are not prime considerations for altering treatment procedures. When the drug is used in short term exposures, Malachite Green may tend to be more toxic to some species in warm water than in cold water. Preliminary experiments have demonstrated that hardness or pH of the water has a negligible effect on increasing or decreasing the toxicity of the drug."
http://www.novalek.com/kpd26.htm
Malachite green goes by many names: Victoria green, aniline green and so forth and is a common ingredient in many ich medications. There are also cautions on their web site for their products that contain formalin, another commonly used ich medication.
The Kordon web site is a gold mine of medication information. Read their Product Data Sheets. I've read most of them by now and I am totally *shocked* at what other manufacturers, like Jungle, do not tell you about the chemicals they put in their prodcuts.
Remember, Kordon
makes this stuff. They don't gain anything but consumer education by putting this all up for the public.
http://www.novalek.com/kpds.htm
Roan