I doubt it, IME pixies get along with agressive and semi-agressive fish, but they're NASTY with any fish that's a pushover. Mine is constantly testing his tankmates (dottyback, angels, sixline & damsels), taking runs at them, but all they need to do is give him a little attitude and he backs down. They're a lot of talk, not so much action as long as the other fish is fairly tough.