As I remember it(just barely), you have a 20 gal. with pretty good kH, correct?
You could put two bottles up on the tank and change one every 10 days for a good, continuous flow.
If you stick with one bottle, you can expect a fall-off in injection(a rise in pH will tell you) in about 10 days or so. I would suggest mixing a new batch and replacing bottles at 9 - 10 days, unless you have super yeast(champagne).
I used to use baker's yeast and all I got was 10 days for good flow. You can hold off, but it will probably cause fluctuation in pH if you do.
What are you using to seal the cap where the tubing comes out?
Len