go slowly and test
We expect that DIY will not get too much CO2 in the tank, but I've still seen it done with too large generators and too much yeast. So, start slow, then make improvements as you get it all working.
It does take some time for the fish to adjust, I believe their blood chemistry has to actually adapt to the changes. Generally, you just want to go slowly. Typically, with a DIY system and a pH of 8.0, which I assume means a KH of 9 or better, you will not be able to get into a danger zone.
Still, to be safe, don't over do the mix at the start. After everything is running smoothly, test the pH and KH and check a Co2 chart to see if you are near the target 25 ppm of CO2. While you are looking at the chart, determine the minimum pH that is wise, so that you will know that, for example, if you pH goes to 6.6 you have too much CO2, as well as the target pH you are hoping to get.
As you go along, you will try to improve the initial rate and the lifespan of the mixture, as well as reduce the surface losses due to agitation and improve the efficency of the CO2 absorbtion.
Best to start it on a day when you have time to watch the fish for stress, and to be sure nothing foams up and into the tank. So, not too late at night, start on a day when you'll be around. If you are concerned that the rate may be high and the fish may be stressed by morning, add an airstone overnight and remove in the morning when you can watch.