with reef crystals i don't use calcium in between water changes, because levels are always good. so, i guess it would save you some money if you would have corals. also note that with RC you will not need to use buffers for alkalinity or ph, which i can't say the same about IO. in fact, when i used IO i always had to add ph buffer. i don't have a need in ph buffer anymore, so more stuff that i woudn't have to buy. also fish needs vitamins in the water and in food, but you'll save on vitamins too, because you will only need it for the food and not the water with RC.