You question, I have wondered about.
I used to work for Occidental Petroleum in the 1980's--their Ag Chem division--I was head of inventory control. We used to spread Calcium Sulfate on agricultural land, not only was this a cure for too acid a soil, it was also a cure for too alkaline a soil. And, of course, it would leech sodium down below where crop roots could pick it up and it stave off it having a negative effect on plant growth.
So, naturally, I have wondered about it as a buffer in aquariums. Too acid and it would "absorb" much of that effect ... too alkaline and it would "absorb" (or buffer these) this also ...
I mean, if it worked in fields, why not aquariums? By the way, calcium sulfate is gypsum--you can get this from smashing up sheetrock ... the material between the layers of "cardboard" is gypsum "calcium sulfate."
Regards,
JS