I was doing some research on the internet about flukes, and Prazi and best treatment options, etc. What I read on at least 2 different pond websites, was that Prazi in combination with malachite green/formalin is a so called "Silver Bullet" and will kill just about any parasite that the fish has. One website talked about mixing prazi powder with Pro-form C (malachite green/formalin) just to get the powder to dissolve--the directions with the prazi actually recommended it. And, Hakari, the makers of Prazi-Pro, have a link on their website that says "Excellent When Used With Ich-X" which is formalin/safer salt of malachite green combo. Here is the link to the ad:
http://www.uskoi.com/prazipro.htm
I think it is funny, because on the back of the prazi-pro bottle, it says do not combine with any other drugs or meds. But, Hikari's website recommends otherwise. Also, like I said, several pond websites recommend the combo since when in powder form, prazi is really hard to dissolve. So, I am thinking of getting myself some more Prazi-pro to continue treatment, and maybe use in combo with formalin/malachite green at the recommended dose and see if that will knock the flukes out. I wonder if I would get better results with that? I tried them in combo in one of my tanks last night (not the main one I was trying to treat but another one that I am worried about contaminating from the first one). I noticed one or two fish in that tank that were questionable and when I saw one flash quickly, I knew I had to act fast so I don't end up with a catastrophe like in my big tank that I am dealing with. I treated last night with Prazi in combo with quick cure (malachite green/formalin) and they seemed fine last night and no flashing after adding it. The two fish that were breathing heavy seemed more responsive this morning, but didn't see them eat yet. So, I will watch that tank very closely over the next few days, and if all looks well, I will stick with the combo treatment.
I have to go on a trip and will be gone for a week (leaving in about 1 1/2 to 2 weeks). So, I am thinking of doing the combo treatment up till that point. And, during the week that I am gone, just leaving the prazi in there. Either Prazi or trichlorfon (which was not working for me as of late) are the 2 that are passive treatments that you can dose and leave for a few days without being there to add meds or do water changes every day. That is what I need while I am gone, so if the prazi is working by then, that is what I will do.
The fish in my main tank that I am having problems with, responded good to the prazi after I cranked up the heat yesterday. The heavy slime disappeared off them (still a couple noticeable spots though) but some were still flashing which bothers me. That tells me that there are adult flukes still attached to the fish. Prazi is suppose to be fast working and sometimes only 2 days is needed to kill flukes from the fish (longer of course for emerging larvae from the eggs). So, maybe I should dose higher than the recommended? I am trying to give it time, but have been treating with Prazi since Thursday. I know it is hard to overdose that stuff because it is gentle. I have left in the sponge filters in the tank, but there is no carbon present, and I scrubbed the glass and vacuumed the gravel very well. I emptied the tank except for a couple decorations for the fish to hide in if need be. So, I don't know what else to do? I hope the combo treatment works. Some have suggested a synergistic effect with the combo of Prazi, malachite green and formalin.