Powerheads blowing sand around can raise phosphate concentration, especially if it disturbs a previously settled deposit. If you keep a relative configuration of water flow, the sand will eventually settle in a stable location. Any significant alteration will sort of reset the process, though.
I don't really recommend stirring at all--not manual stirring, anyway. You should rely on a good number of worms and even smaller organisms to accomplish that for you. Good diversity and good flow across the sand bed will ensure a significantly longer life in the sand bed. Phosphate reduction in the water column also goes a long way in helping with this.