Addendum to my post above: Maracyn and Maracyn 2 are antibiotics that are dosed everyday, and they don't instruct you to do water changes daily, nevertheless, those two products have their immediate beneficial impact after the dose and for a few hours and then break down. There is no cumulative benefit to increasing levels of those two in the tank. Daily water changes and then fresh doses of this combo provide optimum benefit.
If the fish keeper just can not do daily water changes then at least every other day, along with close monitoring of the parameters and dosing with Prime to handle any detectable levels of ammonia or nitrite.
If the fish keeper just can not do daily water changes then at least every other day, along with close monitoring of the parameters and dosing with Prime to handle any detectable levels of ammonia or nitrite.
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