I have never read the back of the heat pack bags thoroughly before. Today while packaging boxes I did. I did not realize the heatpacks can only raise temp 10-12 degrees within a cubic foot insulated box. You have to use multiple warmers to increase temp more than that. I typically do at least 2 anyway but this information makes it clear that I need to use at least 4 for shipping fish this time of year. I found this info really helpful and figured I would share. Also it states that the warmer will stop generating heat if the temp inside the shipping box falls below freeing which is interesting. Uniheat recommends usin double boxing with insulation an dheat packs between the double boxes.