Is there anything in there providing water movement? That will be important, since the oxygen in the water is replenished via surface agitation, usually from water returns or movement through filters.
Rather than randomly changing 25%, the better solution is to test the water and do changes large enough to keep the ammonia and nitrates as close to 0 as possible. While the filter contains most of the bacteria, all the solid surfaces in the tank will house some bacteria. These populations will expand to take up the slack, but this will be a slow process (days or weeks), so big water changes will be best.
If you didn't have the fry, I'd say to drop the temp and quit feeding, but that won't work here. You can lower the temp a bit, but reducing feedings might result in the loss of some fry, depending on how old they are now.