I believe you can keep a nugget with medusa, and if the tank is big enough with enough wood / caves, a couple of bristlenoses will be fine. I'd watch out more when it comes to feeding, they have different feeding requirements. Nuggets are omnivores and prefer meat with some greens, whereas bristlenoses are primarily herbivorous and prefer veggies & algae.
I have my L018 nugget with a L66 king tiger and 2 bristlenoses, they are fine. But you should not have more than 1 nugget in a tank as they are very territorial amongst their own species.