If it's a new tank, yes - remove any plastic bags, insert spacer, coarse>fine media (rinsed first, it gets a bit dusty during transport) w/ pad between layers, carbon on top (or sponges per directions, assuming you got one w/ some sort of media/sponge kit), add top spacer, water, seal (careful not to nick the big O-ring), hook up hoses, open valves and power it up. It should noisily belch a bunch of air for a little while and then run silently for the rest of your life.
For an established tank (or filter media), do the same as above, but treat water as needed with Prime or whatever conditioner you use.
Many people like to drill a small hole a little below the water line on the filter's intake tube so that in the unfortunate event of a profound filter failure, hose disconnect or whatever, the filter will only drain the tank down to the hole in the intake tube (assuming your sparabar's highest hole is not way below the water line in the tank). I have done this and I keep a little poster putty on the back rim of the tank to seal said hole during water changes (so the filter doesn't suck in any air).