We got my son a 45 gallon tank for his birthday last month. We got two angelfish, a rainbow shark, a small clown pleco and a larger pleco. All was going well until about a week ago. The angelfish would congregate in the top corner of the tank. We checked the temp, water quality, etc. And decided to do a 25% water change. They were fine for about a day and then back to the corner. We were going to purchase new testing strips, and when we came back they were swimming sideways and upside down. We added some tetra safe medication, but they died later that night. The small pleco died the next day. We tested the water again and the nitrites were high so we did another 25% water change and added more medication. Now our rainbow shark is acting odd and has a weird, almost milky white rash. What can we do? Any advice please as my son loves his rainbow shark!