I wish folks would list what country they are in. Esha is common in Europe but not the USA. If what you have is columnaris, this med will not help.
I do not like sending filks to overly scientific references, so i will summarize a bit. Milder strains of columnaris or less advanced stages of some of more virulanet strains can be treated by sosing a proper antribiotic in the water. After things are advance, this will not work, one needs for use medicated food. If a fish is not eating, onjection is the last resort and most of us cannot find, prepare or administer meds this way.
There is a weed killer that has proved effective, but this is not for folks new to the hiobbby and with no experience with "toxic" stuff should mess with this stuff. I believe procuring fish antibiotics in the UK and the rest of Europe requires a prescription from a vet.