does bio-spira work good with stresscoat? i just started my fishless cycle and i used stress coat then usec bio-spira when igot a ammonia readingicecubez189 said:i use Prime as well, only switched to it because i wanted to cycle with Bio-Spira, and they only work well with either Bio-Safe or Prime. so far its great, very concentrated although i think i use too much during my water changes so i've adjusted accordingly.