Actually they are both very similar, one just using a way more "modern" way of altering the genes in a way that makes the fish more attractive. In my opinion those fancy goldfish are just as bad if not worse, so why arent people sooo against those. First off, its all "manipulating" genes, and seccond the way the genes have been manipulated in the goldfish make life hard on the fish even in the home aquarium, where as the glofish dont have any less quality of life than a regular danio. That said I wouldnt buy any, I dont find them attractive, and to whoever said that if another fish eats a glofish they will get it....wrong thats not how genes work. Getting loose and breeding in the wild, is highly unlikely IMO, first off even 2 glow fish only produce 50% glowing babies, and the chance that 2 glowfish meet in the wild, that havent been eaten for the fact that they couldnt hide, is very unlikely....and glowing fry have little chance of survival in the wild. Just my .02 though