It looks like you have a planted tank, if so you know that becasue your aquatic plants sit in an ambient surroundings you need to have special substrate with concentrated nutrients available to the roots to make those aquatic plants grow lush and healthy along with CO2 which is in short supply in water. Although Pothos roots will float grow out of a tank you will not get as good a growth results (lush, healthy) since they also will need additional concentrated nutrients closely available, that is where the HOB comes into play as it both brings and concentrates most all the nutrients suspended in the water directly to and across the roots many times faster and repetedly several time a day, then the roots alone can catch floating around. Like hydrobotanical sewage treatment plant which are in use around the 3rd world, to be effective all the waste water must be bottle-necked to the plants to be effective. Otherwise people could just float a Pothos in their toilet bowl.
So the answer is yes they will grow but the results will not be the same. Also I would commit to either aquatic plants or hydroponics for 1 aquarium, but I would not do both unless it was a large pond otherwise they will be competing for nutrients.